فريتس ليپمان

Fritz Albert Lipmann

Portrait of Fritz Albert Lipmann (1899-1986), Biochemist (2551001689).jpg
وُلِدَ(1899-06-12)يونيو 12, 1899
Königsberg, German Empire
(present-day Kaliningrad, Russia)
توفييوليو 24, 1986(1986-07-24) (aged 87)
القوميةGerman-American
أسماء أخرىFritz Lippmann
التعليم
عـُرِف بـCo-discoverer in 1945 of coenzyme A
الزوجElfreda M. Hall Lipmann (m. 1931)
الأنجال1
الجوائز
السيرة العلمية
المجالاتBiochemistry
الهيئات

فريتس ألبرت ليبمان (إنگليزية: Fritz Albert Lipmann، و. 12 يونيو 1899 - ت. 24 يوليو 1986)، هو كيميائي حيوي أمريكي-ألماني. ولد ليبمان في كونيغسبيرغ بألمانيا لعائلة يهودية، ودرس الطب في جامعات كونيغسبيرغ وبرلين وميونيخ. عام 1945 اكتشف بالاشتراك كوانزيم أ. وحصل على هذا الاكتشاف مع بحث آخر أجراه حول كوانزيم أ، على جائزة نوبل في الفسيولوجيا أو الطب عام 1953 (تقاسمها مع هانز أدولف كريبس).[1]

النشأة والتعليم

Lipmann was born in Königsberg, Germany, to a Jewish family. His parents were Gertrud (Lachmanski) and Leopold Lipmann, an attorney.[2]

Lipmann studied medicine at the University of Königsberg, Berlin, and Munich, graduating in Berlin in 1924. He returned to Königsberg to study chemistry under Professor Hans Meerwein. In 1926 he joined Otto Meyerhof at the Kaiser Wilhelm Institute for Biology, Dahlem, Berlin, for his doctoral thesis.[3] After that he followed Meyerhof to Heidelberg to the Kaiser Wilhelm Institute for Medical Research.

السيرة

From 1939 on, Lipmann lived and worked in the United States. He was a Research Associate in the Department of Biochemistry, Cornell University Medical College, New York from 1939 to 1941. He joined the research staff of the Massachusetts General Hospital in Boston in 1941, first as a Research Associate in the Department of Surgery, then heading his own group in the Biochemical Research Laboratory of the hospital. From 1949 to 1957 he was professor of biological chemistry at Harvard Medical School. From 1957 onwards, he taught and conducted research at Rockefeller University, New York City.

In 1953, Lipmann received one half of the Nobel Prize in Physiology and Medicine "for his discovery of co-enzyme A and its importance for intermediary metabolism." The other half of the award was won by Hans Adolf Krebs.[4] Lipmann was awarded the National Medal of Science in 1966. He would try to dive further into his discovery by finding a variant of co-enzyme A, now known as Pantethine. He was an elected member of the American Academy of Arts and Sciences,[5] the United States National Academy of Sciences,[6] and the American Philosophical Society.[7]

Lipmann introduced the specific squiggle designation (~) to indicate high energy-rich phosphate in energy-rich biomolecules like ATP in his essay "Metabolic Generation and Utilization of Phosphate Bond Energy."[8] Of his work, he said "that in the field of biosynthesis we have a rare example of progress leading to simplification."[9]

الحياة الشخصية

ليبمان مع ماري سومز في ستوكهولم في 1953

In 1931, Lipmann married Elfreda M. Hall. They had one son.[2] Lipmann died in New York in 1986.The photo shows Mary Soames, not Elfreda Hall Lipmann[10] توفيت أرملته في 2008 عن عمر 101.

انظر أيضا

وصلات خارجية

قالب:1953 Nobel Prize winners

  1. ^ Jencks, W. P.; Wolfenden, R. V. (2000). "Fritz Albert Lipmann. 12 June 1899 -- 24 July 1986: Elected For.Mem.R.S. 1962". Biographical Memoirs of Fellows of the Royal Society. 46: 333. doi:10.1098/rsbm.1999.0088.
  2. ^ أ ب "Fritz Lipmann – Biographical". Nobel Prize.
  3. ^ Krebs, Hans A.; Lipmann, Fritz (1974). "Dahlem in the Late Nineteen Twenties". In Richter, Dietmar (ed.). Lipmann Symposium. Energy transformation in biological systems. Berlin: Walter De Gruyter. pp. 7–27. ISBN 9783112316269.
  4. ^ "The Nobel Prize in Physiology or Medicine 1953". NobelPrize.org (in الإنجليزية الأمريكية). Retrieved 2019-08-07.
  5. ^ "Fritz Albert Lipmann". American Academy of Arts & Sciences (in الإنجليزية). Retrieved 2022-12-08.
  6. ^ "Fritz Lipmann". www.nasonline.org. Retrieved 2022-12-08.
  7. ^ "APS Member History". search.amphilsoc.org. Retrieved 2022-12-08.
  8. ^ "Fritz Lipmann Facts". biography.yourdictionary.com. Retrieved 2019-08-07.
  9. ^ The Rockefeller University (1950-01-01). "Fritz Lipmann, 1948". Harvey Society Lectures.
  10. ^ FRITZ A. LIPMAN, BIOCHEMIST, DIES. New York Times (August 16, 1986)
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