علم الجينوم البنيوي
(تم التحويل من Structural genomics)
علم الجينوم البنيوي Structural genomics، هو علم يبحث في وصف البنية ثلاثية الأبعاد لأي بروتين عن طريق الجينوم.
الأهداف
الأساليب
de novo methods
Modelling-based methods
ab initio modeling
Sequence-based modeling
Threading
أمثلة على علم الجينوم البنيوي
The Thermotogo maritima proteome
The Mycobacterium tuberculosis proteome
قواعد بيانات وتصنيفات بنية البروتين
انظر أيضا
المصادر
- Hooft RW, Vriend G, Sander C, Abola EE (1996). "Errors in protein structures". Nature. 381 (6580): 272. doi:10.1038/381272a0. PMID 8692262.
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ignored (help)CS1 maint: multiple names: authors list (link) - Marsden RL, Lewis TA, Orengo CA (2007). "Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint". BMC Bioinformatics. 8: 86. doi:10.1186/1471-2105-8-86. PMC 1829165. PMID 17349043.
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: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link) - Baker EN, Arcus AL, Lott JS. 2003. Protein structure prediction and analysis as a tool for functional genomics. ‘’Applied Bioinformatics’’ 2(3 Suppl):S3-S10.
- Goulding CW ‘’et al’’. 2003. Structural genoimcs of ‘’Mycobacterium tuberculosis’’: a preliminary report of progress at UCLA. ‘’Biophysical Chemistry’’ 105: 361-370.
- Lesley SA ‘’et al’’. 2002. Structural genomics of the ‘’Thermotoga maritima’’ proteome implemented in a high-throughput structure determination pipeline. ‘’PNAS’’ 99(18):11664-11669.
- Skolnick J, Fetrow JS, and Kolinski A. 2000. Structural genomics and its importance for gene function analysis. ‘’Nature Biotechnology’’ 18:283-287.
وصلات خارجية
- Structural Genomics Consortium
- Protein Structure Initiative (PSI)
- PSI Structural Genomics Knowledgebase: A Nature Gateway
- Northeast Structural Genomics Consortium
- The Midwest Center for Structural Genomics
- Berkeley Structural Genomics Center
- Center for Eukaryotic Structural Genomics
- Yeast Structural Genomics (Genomique Structurale de la levure)
- RIKEN Structural Genomics/Proteomics Initiative
- Structural Genomics of Pathogenic Protozoa
- The Joint Center for Structural Genomics
- Mycobacterium tuberculosis Structural Genomics Consortium
- New York SGX Research Center for Structural Genomics (NYSGXRC)
- NJCST Initiative in Structural Genomics and Bioinformatics
- Structural Genomics at Brookhaven Natl. Labs
- Structure to Function Pilot Project: CARB
- The Southeast Collaboratory for Structural Genomics
- Toronto Structural Proteomics Consortium
- Protein Structure Factory
- Oxford Protein Production Facility
- Seattle Structural Genomics Center for Infectious Disease
- Structural Proteomics in Europe SPINE
- Forum for European Structural Proteomics (FESP)
- Israel Structural Proteomics Center (ISPC)
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